The base stem of this shrub will grow up to 10 inches 25 cm in diameter and produce many woody branches that cling to surrounding flora for support. The inner bark is light and cork like, with yellow sapwood. The leaves are oval shape and grow on singular stems, ranging in color from light to dark green. The flowers are tiny, whitish green to yellow green, and grow on the top of the main stalk. Celastrus is prized by native peoples throughout India for its seeds, which grow in round pods that gradually change from a light yellow to a deep red color as they mature.
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Hormesis: Benefits of Training Your Stress Response Overview: Celastrus paniculatus is an herb used in Ayurvedic medicine with nootropic and neuroprotective effects. It contains several bioactive compounds including sesquiterpenes such as celastrine, celapanine, celapanigine, celapagin, malkangunin and paniculatine.
Celastrus paniculatus has been shown to enhance cognitive function by improving memory and learning, and to protect the brain from oxidative damage and neurotoxicity. Anxiolytic, antidepressant, analgesic and anti-inflammatory effects have also been described. Scientific Name: Mechanisms: Inhibition of acetylcholinesterase activity in the brain. Nootropic activity of Celastrus paniculatus seed.
Pharm Biol. Effects of Celastrus paniculatus on passive avoidance performance and biogenic amine turnover in albino rats. J Ethnopharmacol. Antioxidant property of Celastrus paniculatus willd. Neuroprotective effect of Celastrus paniculatus on chronic stress-induced cognitive impairment. Indian J Pharmacol. Reversal of scopolamine-induced deficits in navigational memory performance by the seed oil of Celastrus paniculatus.
Pharmacol Biochem Behav. Anc Sci Life. Cortico-hippocampal salvage in chronic aluminium induced neurodegeneration by Celastrus paniculatus seed oil: Neurobehavioural, biochemical, histological study. J Pharmacol Pharmacother. Ameliorating effect of Celastrus paniculatus standardized extract and its fractions on 3-nitropropionic acid induced neuronal damage in rats: possible antioxidant mechanism.
Celastrus paniculatus seed water soluble extracts protect against glutamate toxicity in neuronal cultures from rat forebrain. Celastrus paniculatus seed oil and organic extracts attenuate hydrogen peroxide- and glutamate-induced injury in embryonic rat forebrain neuronal cells. Effect of Celastrus paniculatus seed oil Jyothismati oil on acute and chronic immobilization stress induced in swiss albino mice.
Pharmacognosy Res. Celastrus paniculatus seed water soluble extracts protect cultured rat forebrain neuronal cells from hydrogen peroxide-induced oxidative injury. Indian medicinal plants as antiradicals and DNA cleavage protectors. Evaluation of anxiolytic potential of Celastrus oil in rat models of behaviour. Valecha R, Dhingra D. Basic Clin Neurosci. Preliminary screening of methanolic extracts of Celastrus paniculatus and Tecomella undulata for analgesic and anti-inflammatory activities.
Effect of Jyotishmati Celastrus paniculatus seeds in animal models of pain and inflammation. J Ayurveda Integr Med. J Diet Suppl. August Effect of Celastrus paniculatus seed extract on the brain of albino rats. Indian J Clin Biochem. New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus. Planta Med. Identification of a new sesquiterpene polyol ester from Celastrus paniculatus. Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum.
Screening South Indian medicinal plants for antifungal activity against cutaneous pathogens. Phytother Res. Jyothi KS, Seshagiri M. In-vitro activity of saponins of bauhinia purpurea, madhuca longifolia, celastrus paniculatus and semecarpus anacardium on selected oral pathogens. J Dent Tehran. Attenuation of quorum-sensing-dependent virulence factors and biofilm formation by medicinal plants against antibiotic resistant Pseudomonas aeruginosa. J Tradit Complement Med. We are focused on making groundbreaking products for health and well-being through complex systems science.
Celastrus Paniculatus (Jyotishmati Malkangani)
Sciatica Secondary Amenorrhea However, its use in digestive problems is uncommon, but it is also beneficial for chronic constipation, loss of appetite due to decreased secretion or production of gastric juices, intestinal gas and abdominal distension. Its seeds have effects on brain, mind, nerves, joints and bones. Improving Intellect For improving intellect, Celastrus Paniculatus is mainly prescribed and it has memory enhancer action. It also improves concentration, alertness, and other cognitive functions.
Celastrus Paniculatus Seed Extract